Lusamine is the main antagonist of Pokémon Sun and Moon, running the Aether Foundation as its president. Early on in the Generation VII titles, not much is known about the character until the player meets her at Aether Paradise. Lusamine is described as a lovely, beautiful woman who wishes for the protection of all Pokémon, both in and out of Alola. Due to this, Lusamine can be seen as quite motherly, loving all hurt Pokémon as if they were her own children. She seems to have a knack for fashion, stating that her looks are the result of the right outfit and style, and is unhesitant to suggest changes to another's wardrobe.
Lusamine's kindness eventually changed over time, becoming obsessed with Ultra Beasts and neglecting her own children. After dropping her kind facade, Lusamine appears to care not for anyone who does not give her positive attention, blaming her kids and their friends for her own rude and neglectful behavior. Her spiral into selfishness and obsession also resulted in abuse of Pokémon, storing them in her trophy room on Aether Paradise under cryostasis. While under the influence of Nihilego, her emotions become much more abrasive and violent, causing her to lash out at her daughter and the player. Lusamine's daughter, Lillie, makes the statement in Sun and Moon that Lusamine was once a very kindhearted woman before her obsessive nature with Ultra Beasts had taken over. In Pokémon Ultra Sun and Ultra Moon, her relationship with Nihilego is removed, but her obsession remains, instead focusing on the protection of the Alola region and being unmindful of the harm she has caused to others. Her destructive and abusive nature caused both her children, Lillie and Gladion, to leave, each stealing a Pokémon from the foundation before leaving Aether Paradise.
